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The project focuses on preconditioning mesenchymal stromal cells under hypoxic conditions, which simulates the oxygen deprivation seen in tissue damage. This process stimulates the secretion of therapeutic extracellular vesicles enriched with angiogenic factors that facilitate tissue regeneration following acute lung injury. These enhanced extracellular vesicles play a crucial role in promoting recovery from acute lung injuries associated with respiratory diseases.

The study was supported by the InnoHK initiative of the Innovation and Technology Commission of the Hong Kong Special Administrative Region Government to the InnoHK Centre for Immunology and Infection.

Team of School of Public Health, LKS Faculty of Medicine:

Prof. Michael Chi Wai CHAN
Professor

Dr. Rachel CHING
Research Officer

Dr. Angel MA
Research Assistant

Email: mchan@hku.hk, hchng@hku.hk 

Gold Medal with Congratulations of Jury, International Exhibition of Inventions Geneva 2025​