A Next-Generation Sjögren's Disease Platform for Drug Discovery

Sjögren's disease has no approved disease-specific drug; patients suffer from low quality of life and rely solely on decades-old symptom management. This project developed a humanized platform that integrates murine and human immune systems to faithfully replicate human disease. The translational platform has already produced multiple patented drug candidates, forging a direct path from human-relevant discovery to much-needed therapies.

Professor Xiang LIN, Associate Professor, Assistant Director (Knowledge Exchange & Technology Development), School of Chinese Medicine, Li Ka Shing Faculty of Medicine

A Novel Demountable Interlocking Structural Connection (DISC) with Reusability: Between Steel I-Beam and CHS Column

This invention proposes a demountable interlocking beam-to-column connection for steel structures. It adopts factory prefabrication, an all-bolted configuration, and a mortise-and-tenon interlocking design to enable rapid assembly and disassembly. After dismantling, the components can be recovered and reused in new buildings, thereby reducing construction waste and lowering carbon emissions.

Professor Tak-Ming CHAN, Professor, Department of Civil Engineering, Faculty of Engineering
Mr. Jiyuan LI, PhD Student, Department of Civil Engineering, Faculty of Engineering
Dr. Xiaozhou HAN, Postdoctoral Fellow, Department of Civil Engineering, Faculty of Engineering

A Novel Oral Peptide Supplement for Bone Health via Neurosensory Pathways by NeurOssence Bio. Limited

HS2P-10 is a first-in-class oral peptide supplement for bone health, developed at HKU's Department of Orthopaedics & Traumatology. Derived from yam, the small peptide engages the bone-brain axis and Wnt/β-catenin signalling, a novel neuro-osteogenic mechanism that supports the body's own bone formation. It uniquely reinforces both bone components: calcium phosphate and type-1 collagen. Preclinical studies show improved bone density and microstructure with no in-vivo toxicity. One 2.4 mg capsule daily.

John Kubi Akrofi, Research Assistant Professor, Department of Orthopaedics and Traumatology

A Portable Device for Non-Invasive and Rapid Cancer Detection Using AI-Powered Optical Sensing / Laboratory for Synthetic Chemistry and Chemical Biology Limited

This invention is a portable device for rapid, non-invasive cancer risk assessment. It detects DNA damage levels in saliva using innovative luminescent metal compounds and a miniature spectral sensor. Its detection can be completed within 10 minutes anywhere with the help of a mobile phone app, requiring no professional medical skills. It provides a routine and convenient approach to evaluate cancer risk.

Professor Chi Ming CHE, Managing Director, Laboratory for Synthetic Chemistry and Chemical Biology Limited (LSCCB)
Dr. Wei LIU, Scientist, Laboratory for Synthetic Chemistry and Chemical Biology Limited (LSCCB)

AI Policy and Literacy in Education

Professor Cecilia Chan’s work supports the responsible integration of GenAI into education through policy frameworks, AI literacy courses, teacher workshops, practical guides, and assessment innovations. Her research informs AI education policy, strengthens students’ and teachers’ AI literacy, and promotes ethical, effective use of AI across higher education and schools.

Professor Cecilia Chan, Professor, Teaching and Learning Innovation Centre (TALIC), Faculty of Education, AI in Education Lab

Learn more: https://aiedlab.hku.hk/

AI-Assisted Oral Health Screening and Education: Promoting Awareness and Preventive Care for Hong Kong's Elderly Population

This project develops GumAI, an AI-powered system that detects gum disease using smartphone photos of the mouth. Beyond preventing tooth loss, early detection reduces the risk of linked systemic conditions like diabetes. The tool offers site-specific assessments and personalised hygiene advice, supporting remote monitoring from home for Hong Kong’s elderly. Clinically validated and used in community screening, GumAI empowers elderly people to improve oral health awareness and contributes to preventive oral health on a broader scale.

Professor Walter LAM, Clinical Associate Professor, Faculty of Dentistry

Learn more:
https://facdent.hku.hk/publications/2025-summer/senior.php

https://www.ke.hku.hk/story/video/dental-ai

https://www.ke.hku.hk/spotlight/transforming-dental-care-the-social-impact-of-dentomi-s-ai-technology

AiCore for Artificial Intelligence Logistic Scheduling and Transport Monitoring of Prefabricated Building Modules Manufactured Offsite for Just-in-Time and Safe Onsite Assembly

AiCore is the first Agentic Artificial Intelligence of Things (AIoT) that integrates autonomous AI agents with our award-winning iCore IoT hardware attached to prefabricated building modules to collect their real-time location, vibration, temperature, and humidity information for real time dynamic scheduling, transport monitoring, accurate arrival predictions, and proactive vibration alerts for of the transport of offsite manufactured prefabricated building modules to be assembled in construction sites just-in-time and safely.

Lu, Wilson W.S., Chair Professor, Department of Real Estate and Construction, Faculty of Architecture, HKU
Yeh, Anthony G.O., Chair Professor, Department of Urban Planning and Design, Faculty of Architecture, HKU
Hong Kong Housing Authority
Wu, Liupengfei, Assistant Professor, Division of Industrial Data Science, School of Data Science, LingnanU
Zhang, Yi, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU
Zou, Yuanben, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU
An, Hongda, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU
Peng, Ziyu, Post-doctoral Fellow, Department of Real Estate and Construction, Faculty of Architecture, HKU
Gao, Yuchen, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU

Learn more: https://ilab.hku.hk/project/aicore/

AI-Powered "Super-Scanner" to Revolutionize Precise Gene Editing

This project develops an AI-powered CRISPR platform to overcome low efficiency and off-target effects in gene editing. Tools CombiSEAL and TopVIP screen millions of variants, using less than 1% of data to predict top designs. Testing across 64 million variants doubled success rates with zero bystander edits. Published in leading journals and protected by patents, this platform advances precision medicine through highly efficient and cost-effective genome engineering.

Professor Alan Wong, Associate Professor, School of Biomedical Sciences, Faculty of Medicine

AI-Powered Instant Feedback System for Ultrasound Skills Assessment

Ultrasound training is crippled by a global instructor shortage, leaving students without real-time feedback during independent practice. This cloud-based AI platform closes that gap, analysing renal ultrasound images in under 800ms with 93.1% accuracy, delivering instant feedback on probe placement, brightness, and artefacts. Currently operational at HKUMed, it transforms manual instruction into scalable digital infrastructure alongside a companion Android app for low-connectivity environments, standardising student readiness and enabling faculty to focus on clinical mentorship while AI handles skill validation.

Dr. Rahul Singh, Post-Doctoral Fellow, Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong
Professor Elaine Yuen-Phin Lee, Clinical Associate Professor, Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong
Mr. Cheuk Nam Hwang, Research Assistant, Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong
Professor Michael Tiong-Hong Co, Clinical Associate Professor, Department of Surgery, School of Clinical Medicine, The University of Hong Kong

Learn more: https://usrenalhkumed.azurewebsites.net/

Air Ring 49: Contactless Biomedical Cooling Accessory for Outdoor Workers by Hay-koze Limited

The Air Ring 49 was developed for outdoor workers who face significant heat-related health risks. At just 155g, it is tested to cool critical head hotspots by up to 5.1°C, operates contactlessly, delivers up to 15 hours of power, and adapts to any helmet using a proprietary Smart-lock system. Unlike bulky waist fans or cooling jackets, it is ergonomic, agile, and maintenance-free, while also functioning as a neck cooler. With over 400 units ordered by major contractors and recognition from the James Dyson Award, Air Ring 49 pioneers a new standard of contactless safety for hot environments.

Li Ze Fu Jeff, Alumnus, Department of Architecture, Faculty of Architecture (Chief Operating Officer of Hay-koze Limited)
Ju Wai Hang (Mac), Alumnus, Department of Architecture, Faculty of Architecture (Chief Product Officer of Hay-koze Limited)
Mak Yu To (Vito), Alumnus, Department of Electrical and Computer Engineering, Faculty of Engineering (Electronics Engineer of Hay-koze Limited)

Learn more: https://haykoze.wordpress.com/

ANIWARE Company Limited

Aniware is a Hong Kong startup redefining pet care through AI and data solutions. By connecting the fragmented pet care journey across home, veterinary clinics, and specialist hospitals, Aniware turns veterinary ECG into scalable AI-powered diagnostics and monitoring through its flagship product, CardioBird.

Dr. Joe MAK, Founder & CEO, ANIWARE Company Limited

Learn more:
https://www.aniware.ltd/

https://www.cardiobird.com/

Archireef Limited

Dr. Vriko Yu, Co-Founder & CEO, Alumni HKU
Professor David Baker, Co-Founder; Professor, School of Biological Sciences, Faculty of Science, HKU

Learn more: https://archireef.co

BioEcho

BioEcho is the world's first AI-powered wearable echocardiography platform. It miniaturizes conventional ultrasound machines into a coin-sized device integrated with flexible sensors and advanced AI algorithms to deliver radiation-free, real-time, 24/7 heart monitoring. The device can be worn during daily life, exercise, elderly care, or clinical nursing, enabling early detection and timely intervention in cardiovascular disease.

Angel Yau

Learn more: http://www.bioecho.hk/

CEDARS / The Innovation and Technology Commission

Launched by the Innovation and Technology Commission in 2020, the STEM Internship Scheme aims to encourage STEM students to gain innovation and technology (I&T)-related work experience during their studies and to foster their interest in pursuing a career in I&T after graduation, thereby enlarging the local I&T talent pool.

Centre for Translational Stem Cell Biology

The success rate of clinical trials in drug development remains low, with approximately 90% of drugs failing during human trials due to the complex differences in human biology. Additionally, around 98% of medications lack comprehensive maternal-fetal safety policies. This innovative solution uses EPSCs generated from just 3-4 drops of blood, which are mutation-free and highly programmable, as biological siblings for testing. Their totipotent ability allows differentiation into all cell types and placental-like tissues, enabling more accurate safety assessments and accelerating drug discovery and safety testing.

Professor Pengtao LIU, Professor, Centre for Translational Stem Cell Biology

CereThera Limited – NanoPowder Nasal Spray for Rapid Stroke Rescue

This award-winning project develops the NanoPowder Nasal Spray, an innovative prehospital stroke solution with rapid onset and universal eligibility. By integrating nanotechnology, particle engineering, and inhalation sciences into a "Nano-in-Micron" technology platform, it achieves nose-to-brain delivery to bypass the blood-brain barrier, providing early neuronal protection to reduce stroke-related damage. Preclinical studies demonstrated rapid neuroprotection around the ischemic core and preservation of motor functions. This groundbreaking therapy could significantly improve stroke care by enabling timely intervention outside hospital settings.

Professor Aviva S.F. CHOW, Associate Professor, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine
Dr. Zitong SHAO, Post-doctoral Fellow, Advanced Biomedical Instrumentation Centre; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine
Ms. Yinjie ZHOU, Research Associate, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine
Ms. Jiahui DENG, Research Assistant, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine

Learn more: https://www.linkedin.com/company/cerethera-limited/

CereThera Limited (A Spin-off of InnoHK ABIC) – NanoPowder Nasal Spray for Rapid Stroke Rescue

This award-winning project develops the NanoPowder Nasal Spray, an innovative pre-hospital stroke solution with rapid onset and universal eligibility. By integrating nanotechnology, particle engineering, and inhalation sciences into a Nano-in-Micron platform, it achieves nose-to-brain delivery that bypasses the blood-brain barrier and provides early neuronal protection. Preclinical studies demonstrated rapid neuroprotection and preservation of motor function, supporting timely stroke intervention outside hospital settings.

Professor Aviva S.F. CHOW, Associate Professor, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine
Dr. Zitong SHAO, Post-doctoral Fellow, InnoHK Advanced Biomedical Instrumentation Centre; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine
Ms. Yinjie ZHOU, Research Associate, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine
Ms. Jiahui DENG, Research Assistant, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine

Learn more: https://www.linkedin.com/company/cerethera-limited/

CraftscapeHK: Bringing Hong Kong Heritage to the World

CraftscapeHK is an AI-assisted craft-tourism and cultural-commerce platform connecting Hong Kong heritage artisans with global travellers. Visitors use culturally grounded AI to co-design bespoke crafts, preview them in AR, follow real-time cultural itineraries, communicate across languages, and book hands-on workshops. Artisans remain the creative masters while gaining direct commissions, teaching income and international visibility. By turning passive sightseeing into participation and purchase, CraftscapeHK makes heritage preservation economically sustainable.

Ms. Yuen Tin Yan, Grace, Co-Founder; Year 3, BEng (Computer Science), Faculty of Engineering, The University of Hong Kong

Learn more: https://craftscape.studio/

DeepSonix Limited

DeepSound develops an array-based ultrafast ultrasonic inspection system for IC defect detection. Using multi-channel parallel acquisition, it cuts scan time from tens of minutes to seconds, enabling 100% online wafer inspection to boost yield and reduce manufacturing costs. Dynamic beamforming with adjustable waveforms and focal positions detects micron-level defects in both traditional packages and advanced 3D stacks, breaking the speed-precision dilemma that plagues current inspection tools.

Professor Wei-Ning LEE, Deputy Head, Associate Professor, Department of Electrical and Computer Engineering, Faculty of Engineering

Learn more: https://deepsonix.github.io/#home

Delonix Bioworks

Founded by Professor Jiandong Huang and Dr. Lin Qiubin, Delonix Bioworks is a clinical-stage biotechnology company pioneering the development of next-generation bacterial vaccines. Leveraging its proprietary synthetic biology and engineered vaccine technology platform, the company is advancing a diversified pipeline targeting critical unmet needs such as meningococcal disease, pertussis, and Neisseria gonorrhoeae infection. Among these, its Group B meningococcal OMV vaccine DX-104 is the first engineered OMV vaccine in China to receive approval for clinical development.

Dr. Qiubin Lin, CEO
Dr. Ming-Chun Lee, R&D Director, Head of Early Discovery
Dr. Chen Dong, Senior Scientist

Learn more: https://delonixbio.com/

Demountable Flooring System for Achieving Circularity in Construction

This invention proposes a demountable system connecting precast slabs to slabs or steel beams via bolted interlocking steel connectors. It adopts a bolted design with interlocking for rapid assembly and disassembly. The connection transfers tensile, shear, and uplift forces, minimises concrete damage, and preserves components for reuse, thereby reducing construction waste and carbon emissions.

Professor Tak-Ming CHAN, Professor, Department of Civil Engineering, Faculty of Engineering
Dr. Peng CHEN, Postdoctoral Fellow, Department of Civil Engineering, Faculty of Engineering
Dr. Jiachen GUO, Postdoctoral Fellow, Department of Civil Engineering, Faculty of Engineering

Development and Commercialization of Wearable Robots for Assisting Older Adults Using Artificial Muscle Technology

This project develops a next-generation wearable robotic exosuit engineered to overcome the rigidity and discomfort limiting assistive devices for older adults. By integrating soft artificial muscle actuators and garment-integrated sensing, the system delivers dynamic assistance for sit-to-stand movements, walking, and balance recovery while preserving comfort and natural mobility.

Professor Ning Xi, Chair Professor of Robotics and Automation

Development of a Simulation Platform and Artificial Intelligent Algorithms for Optimising Operation and Management of Taxi E-hailing Services

This project develops an AI-powered taxi fleet management and dispatching system for Hong Kong. By analysing driver availability, order characteristics and fleet conditions, the system recommends suitable orders to drivers and improves fleet-wide coordination. The technology has been deployed long-term in SynCab’s operating vehicles, demonstrating its practical feasibility, industry acceptance and potential to enhance order matching, operational efficiency, service reliability and passenger experience.

Professor Jintao KE, Assistant Professor, Department of Civil and Computer Engineering, Faculty of Engineering
Dr. Peter WONG, Research Officer, Department of Electrical and Computer Engineering, Faculty of Engineering

Learn more: http://demos.hkusmlab.com:3002/simulation-platform

Diversity, Equity, Inclusion, Justice and Belonging Laboratory

The DEIJB Lab develops research-driven, context-responsive resources that foster inclusion in everyday interactions and institutional systems. Co-created with marginalised women, youth, educators, and community stakeholders, its initiatives support meaningful policy and practice change in schools and organizations. The Lab produced Journey With Me Through Hong Kong, My Home, Hong Kong’s first interactive children’s activity book, and Echoes of Home, the first collective anthology celebrating South Asian lived experiences. Through innovative tools and growing educator and youth networks, the Lab equips schools to challenge bias, advance inclusive pedagogy, and cultivate belonging for all students.

Professor Puja KAPAI, Associate Professor, Faculty of Law

Learn more: deijblab.hku.hk

Do Did Dust Food Limited

Do Did Dust Food innovates the circular food economy by upcycling okara, a by-product of soy milk production, into craveable snack chips called Okara Chips. The technology captures the nutritional benefits of high-fiber soy pulp while eliminating the need for MSG or artificial flavoring. By merging sustainable manufacturing with gourmet flavour profiles, the company provides a guilt-free, eco-conscious snacking experience and demonstrates that sustainability can be delicious.

Ms. Cherry LEE, Co-founder & HKU Alumni, Faculty of Science

Learn more: https://dodiddustfood.boutir.com/

DotofAI

Dotof is an AI employer-candidate matching platform that connects the right employers with the right talent through intelligent sourcing, deep matching and verification. By analysing candidates with recruiter-level reasoning and validating skills through realistic job-simulation assessments, Dotof generates explainable and evidence-based hiring recommendations.

Rachel Ko

Learn more: https://dotof.ai

DueSphere AI Limited

DueSphere AI provides an AI-powered due diligence platform that helps multinational brands automate labour risk detection and compliance monitoring across global supply chains. By centering worker voice and continuously surfacing risk signals directly from the ground, the platform transforms fragmented data into actionable intelligence. This enables brands to detect issues earlier, respond faster, and move from checkbox compliance to meaningful worker protection.

Mr. Paras KALURA, Senior Research Assistant, Faculty of Business and Economics
Professor David BISHOP, Associate Professor of Teaching, Faculty of Business and Economics
Ms. Isla WILSON, PhD Student, Department of Sociology, Faculty of Social Sciences

Learn more: https://duesphereai.com/

Dynano Semiconductor Technology Co., Ltd.

Dynano's invention is the world's first solid-state copper sintering technology (SolidCu®), specifically engineered to solve the critical overheating bottleneck in high-power semiconductors. By leveraging nanocrystalline surface activation, it achieves 65% higher thermal conductivity than traditional materials. Coupled with modular all-copper Standard Cells, this technology enables ultra-dense 3D stacking for AI data centres and EV infrastructure. The solution eliminates performance throttling, significantly enhances system safety, and anchors Hong Kong's first independent third-generation semiconductor value chain.

Professor Mingxin HUANG, Professor, Department of Mechanical Engineering, Faculty of Engineering

Learn more: https://www.dynano.com

Eat100 Limited

This project develops a mobile application that allows restaurants to list surplus food from the day on the platform, enabling customers to purchase it at discounted prices. Customers save money while enjoying quality meals, and restaurants generate additional revenue from food that would otherwise go to waste. Most importantly, the app promotes environmental sustainability by significantly reducing food waste.

Anson Wong, Director

eCheckGo: A large defect model-driven AI system for ultra-fast and scalable building inspection in high-density cities

This invention introduces eCheckGo, an AI system driven by a large defect model (LdM) for mass building inspection. It takes up two long-standing challenges in high-density contexts: (a) the time-consuming nature of manual inspections, and (b) the difficulty of case-specific AI training. At the core is our proprietary LdM, a multi-modal large language model tailored for building inspection. Powered by LdM’s strong generalizability, eCheckGo delivers ultra-fast assessments (10s for an entire building) and exceptional adaptability.

Chen, Junjie, Assistant Professor, Department of Real Estate and Construction, Faculty of Architecture
Lu, Wilson W.S., Chair Professor, Department of Real Estate and Construction, Faculty of Architecture
Zhong, Junping, Post-doctoral Fellow, Department of Real Estate and Construction, Faculty of Architecture
Fu, Yonglin, PhD student, Department of Real Estate and Construction
Zou, Yuanben, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture

ESSAA Limited – Creato

Alex Tong, Co-Founder & Chairman

Learn more: https://creatogether.app

Farmacy Group 水耕細作: Smart Mobile Farm & Sustainable Urban Food Network

Farmacy is an award-winning urban ag-tech pioneer revolutionizing food systems through data-driven vertical farming and cloud-based smart infrastructure. Headquartered in Hong Kong and expanding globally, including Australia, it deploys automated, IoT-powered growing systems across more than 50 urban sites. By integrating real-time analytics and environmental controls, Farmacy empowers modern cities to address food security while delivering measurable ESG impact, including reducing water usage by 90%, transport carbon emissions by 70%, and food waste by 30%.

Huen Chun Kit, Co-founder & CTO
Mak Ka Chun Raymond, Co-founder & CEO

Learn more: http://www.farmacyhk.com/

Guiding Clinical Surgery by Intraoperative Infrared Fluorescence Imaging by Beacon IR Medical Ltd)

This project develops next-generation NIR-II fluorescent probes and NIR-II imaging systems to overcome the limitations of conventional NIR imaging. Equipped with proprietary high-brightness water-soluble probes and highly sensitive imagers, the technology enables real-time visualization of tumors and ureters, with strong potential to advance Hong Kong's biomedical sector.

Professor Hongjie DAI, Sapientia Eminence Professor, Department of Chemistry, Faculty of Engineering and School of Biomedical Sciences, University of Hong Kong; J.G. Jackson-C.J. Wood Professor of Chemistry Emeritus, Stanford University

HINCare: AI Solution for Intelligent Volunteer Matching

HINCare is a large-scale data-driven software system that supports volunteering and timebanking. Its advanced AI based on Heterogeneous Information Network (HIN) technology matches needy users and volunteers effectively. It features a user-friendly app and cloud service for data management and analytics. HINCare is now used by 20,000 users and 20 NGOs in Hong Kong, generating social capital estimated at HK$12.4 million. HINCare makes volunteering easy, scalable and affordable while cultivating a mutual-help culture.

Professor Reynold CHENG, Professor, Division Head of AI and Data Science, School of Computing and Data Science

Learn more: https://hincare.hku.hk/

HKU Institute for China Business

The 2026 HKU International Techno-Entrepreneurship Challenge will be divided into a Start-up Track and a Growth Track, with five competition zones including Beijing, Shanghai, Chengdu, Bay Area, and Hong Kong (including Overseas). The competition schedule is divided into four parts: Registration and Preliminary Selection, Empowerment, Preliminary Competition, and Grand Finale. Teams advancing from each competition zone will gather at the University of Hong Kong for an on-site showdown to vie for honours.

Learn more: https://icb.hku.hk/chs/innovalley

HKUMedXelerate - ReMobility

Our vision is to provide affordable, accessible and scalable telerehabilitation solutions to patients worldwide. We developed SmartRehab which is a telerehabilitation platform tracking movements using a mobile device without external sensors. It gives instant feedback to guide patients to undergo rehabilitation exercises at home while therapists can monitor remotely on a web portal. With SmartRehab, patients can greatly enhance their rehabilitation experience and outcome, and therapists can monitor patients more efficiently.

Gary LAU

Learn more: https://remobility.net

Hong Kong Light-Emitting Molecular Materials Limited

This project develops innovative molecular emitters to advance OLED technology, overcoming high material costs and dependence on rare metals such as iridium. Efficient organometallic complexes based on platinum, gold, copper and other metals are engineered across a spectrum from deep blue to near infrared. An integrated AI platform supports high-throughput screening and accelerates material discovery.

Professor Chi Ming CHE, Zhou Guangzhao Professorship in Natural Sciences & Chair Professor, Department of Chemistry, Faculty of Science

Hong Kong Society of Psychological Innovation (HKSPI)

The FLOWER Project is Hong Kong's first technology-driven, "for youth, by youth" school-based psychoeducation initiative targeting holistic wellbeing and suicide prevention. In partnership with HKU, FLOWER features a Digital Mental Health VR/Gaming Platform, AI School Needs Identification Engine, and interactive workshops and carnivals. HKSPI also pioneers Hong Kong's first Mental Health Innovation Ecosystem and largest Psychology & Mental Health Fair, while providing youth employment and tech-for-good training pathways.

Kristen Lei, HKSPI Founder & Chairman, Department of Psychology
Michelle Li, HKSPI Board Chair and Honorary Advisor, Registered Educational Psychologist, PhD Candidate at Department of Psychology
Tiffany Yip, HKSPI Vice Chair (Programme and Innovation), HKU Alumni, Department of Psychology

Learn more: http://www.hkspi.co

Hong Kong Universal Biologicals Company Limited (HKUBio)

The COVID-19 pandemic and rapid spread of SARS-CoV-2 highlight the need for next-generation vaccines that induce both systemic and mucosal immunity. Our innovative DelNS1 platform meets this need and can be combined with flu vaccines to target multiple respiratory viruses. Its effectiveness is supported by successful human trials and an approved human-use product. The platform has generated vaccines for seasonal influenza, COVID-19, and Flu-COVID, Flu-RSV, and Flu-hMPV combinations, with candidates advancing for common cold viruses.

Hong Kong University Department of Microbiology (Virologist) Professor Honglin CHEN
State Key Laboratory for Emerging Infectious Diseases, HKU

Learn more: https://www.hkubio.com/

iEarth: AI-Powered Earth Intelligence Platform by Active Cognition Television Limited

iEarth is an AI-powered Earth intelligence platform developed by HKU. Led by Professor Peng Gong, it integrates multi-source satellite, UAV and ground-sensing data and turns complex Earth observation data into actionable insights for disaster prevention, renewable energy operations, climate-risk assessment and ESG management. Its AI engine supports large-scale, near-real-time monitoring and helps decision-makers act faster and more precisely.

Professor Peng GONG, Vice-President and Pro-Vice-Chancellor (Academic Development) and Chair Professor of Global Sustainability, Department of Geography, Faculty of Social Sciences

Learn more: https://www.iearth.hk/

InnoHK Advanced Biomedical Instrumentation Centre (ABIC)

InnoHK Advanced Biomedical Instrumentation Centre (ABIC), established under the Hong Kong Government's InnoHK programme and launched by HKU in 2020, advances biomedical innovation through trans-disciplinary, trans-institutional, trans-regional, and trans-generational collaboration. The Centre drives breakthroughs in biomedical instrumentation that improve patient care, diagnostic accuracy, and medical research capability. ABIC creates societal impact through the commercialization of innovations benefiting patients, clinicians, hospitals, industry stakeholders, governments, scientific communities, and the healthcare ecosystem.

Professor Paddy Kwok Leung CHAN, Centre Co-Director, Associate Professor, Department of Mechanical Engineering, Faculty of Engineering, The University of Hong Kong
Professor Anderson Ho Cheung SHUM, Founding Centre Director and Co-Director, Vice-President (Research); Chair Professor, Department of Biomedical Engineering, Department of Chemistry, Department of Materials Science and Engineering, City University of Hong Kong

KAPIDA

KAPIDA Technology specializes in the R&D and industrialization of NFC smart products. Its core offerings include NFC smart business cards, NFC creative gifts, NFC souvenirs, and NFC scenario-based application solutions such as gallery and museum guided tours. Built on NFC and AI technologies, the products feature contactless interaction, rapid response, dynamic data updates, and intelligent content generation and recommendation. Integrated with Eastern aesthetic design, they combine practicality with collectible value.

Florence Ng, Founder of KAPIDA, HKU Alumni
Tiffany Zhang, Co-Founder of KAPIDA

Learn more: kapidaofficial.myshopify.com

Kodifly Limited

Kodifly delivers end-to-end Construction Intelligence by transforming physical infrastructure into actionable digital realities. Our ecosystem combines continuous 4D LiDAR capture (K4DL-1000) with the SpatialSense AI engine to automate BIM deviation detection and safety compliance. Purpose-built to answer the DEVB TC(W) No. 1/2026 mandate, our Co-supervision Platform integration empowers stakeholders with millimeter-accurate digital twins, accelerating project schedules, reducing rework, and replacing fragmented manual inspections with real-time, millimeter-level spatial intelligence.

Henry Wong, CEO & Co-Founder
Muhammad Saad Anwel, CTO & Co-Founder

Learn more: https://kodifly.com/

Kynetic

This project, Kynetic, is developing a wearable designed to track biomechanics with precision, aiming to eliminate gym injuries and maximize strength training. By utilizing a five-unit IMU system, it maps limb movement in real-time. Through swing-twist decomposition, Kynetic isolates joint bending from rotation to deliver anatomical accuracy regardless of user body type. By comparing live joint angles against optimal form benchmarks, it flags technical errors instantaneously on every repetition for safer, more effective workouts.

Ananye Dayal, CEO, Department of Mechanical Engineering, Faculty of Engineering
Krish Gupta, CFO, Department of Computer Science, Faculty of Engineering
Krish Paras Patel, Chief Design Officer (CDO), Department of Architecture, Faculty of Architecture

Laser Interference Lithography Equipment and Micro/Nano Manufacturing by InterLitho Innovation Limited

This project pioneers laser interference lithography (LIL) to deliver the world's first commercialized nanopatterning equipment for high-end micro/nano manufacturing. By replacing costly and complex lithography with mask-free, large-area interference patterning, the system overcomes barriers in resolution, throughput, and cost. Integrating nanoimprint printing further extends the solution from R&D prototyping to industrial-scale production.

Professor Wendi LI, Associate Professor, Department of Mechanical Engineering, Faculty of Engineering

Learn more: http://www.interlithotech.com/

Liver-in-Cube: Next-Generation Biomimetic Organ for Precision Medicine

Cancer treatment still relies on trial-and-error and often ignores each patient's unique tumour immune microenvironment. Liver-in-Cube is the world's first 3D-bioprinted platform that faithfully rebuilds the liver cancer microenvironment in the laboratory using a patient's own cells and extracellular matrix. It enables rapid screening of personalized therapies and offers a standardized platform for drug assessment and development.

Professor Nancy Kwan MAN, Chair Professor of Transplant Oncology and Immunology, Department of Surgery, Li Ka Shing Faculty of Medicine

Learn more: oncoimmunostics.com

Mastering Human Performance Through Real-Time Molecular Intelligence by LifeSpectrum Technology Ltd (A Spin-off of InnoHK ABIC)

LifeSpectrum, an InnoHK ABIC spin-off, has developed the world's first digital stress hormone monitoring system, enabling users to track their body's chemistry in real time at home. The proprietary platform combines a low-cost smart reader, disposable nanocartridges, and a simple saliva sample to deliver lab-grade results directly to a smartphone. The business model minimizes upfront hardware costs while driving scalable consumable adoption.

Professor Julian Tanner, Professor, School of Biomedical Sciences, LKS Faculty of Medicine, HKU
Dr. William Whitehouse, Postdoctoral Fellow, InnoHK Advanced Biomedical Instrumentation Centre Limited, HKSTP
Dr. Lin Wang, Postdoctoral Fellow, InnoHK Advanced Biomedical Instrumentation Centre Limited, HKSTP

Mastering Human Performance Through Real-Time Molecular Intelligence by LifeSpectrum Technology Ltd

LifeSpectrum has built the world's first digital stress hormone monitoring system, empowering users to track their body's chemistry in real-time at home. Its proprietary platform utilizes a low-cost smart reader, disposable nanocartridges, and a simple, non-invasive saliva drop to deliver lab-grade results directly to a smartphone. The company operates on a highly scalable recurring "Razor and Blade" business model, minimizing upfront hardware costs to drive high-volume consumable adoption.

Professor Julian Tanner, Professor, School of Biomedical Sciences, LKS Faculty of Medicine, HKU
Dr. William Whitehouse, Postdoctoral Fellow, Advanced Biomedical Instrumentation Centre Limited, HKSTP
Dr. Lin Wang, Postdoctoral Fellow, Advanced Biomedical Instrumentation Centre Limited, HKSTP

MiC Trio: Blockchain-enabled digital solution for Modular Integrated Construction (MiC) off-site inspection, en-route monitoring, and on-site supervision

The MiC Trio is a blockchain-enabled digital ecosystem that digitizes the full Modular Integrated Construction lifecycle via three mobile applications. e-inStar captures real-time factory inspections, photos and reports on a secure dashboard for remote quality control. i-Core sensors with e-TranStar deliver live tracking, environmental monitoring and accurate ETAs during transit. e-InstalStar verifies hoisting paths, placement accuracy and installation sequences on site. Together they boost transparency, precision and productivity across production, logistics and assembly.

Lu, Wilson W.S., Chair Professor, Department of Real Estate and Construction, Faculty of Architecture, HKU
Wu, Liupengfei, Assistant Professor, Division of Industrial Data Science, School of Data Science, LingnanU
Peng, Ziyu, Post-doctoral Fellow, Department of Real Estate and Construction, Faculty of Architecture, HKU
An, Hongda, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU
Zou, Yuanben, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU
Zhuang, Yaoliang, PhD Candidate, Department of Real Estate and Construction, Faculty of Architecture, HKU

Milla's Fizz

Milla's Fizz is a handcrafted natural fermented probiotic soda made in small batches using traditional fermentation methods. Made with real fruits, fresh botanicals and live cultures, the beverages are designed to be both healthy and delicious. Every bottle is naturally fermented, contains live probiotics, is cold-pressed, caffeine-free, free from artificial additives, and produced in small batches for maximum freshness.

Camilla

Learn more: https://www.drinkmillas.com

Mindful Sparks

Mindful Sparks was founded in 2021 by Winston Lau. With a background in nutrition and food science from The University of Hong Kong, he thoughtfully brings together the artistry of tea and scientific innovation. He was also named to Forbes 30 Under 30 Asia in 2025. Mindful Sparks crafts sparkling tea for a luxurious dining experience, elevating tea heritage while promoting a mindful drinking culture grounded in wellness and a non-alcoholic lifestyle.

Winston Lau, CEO, Founder of Mindful Sparks

Learn more: https://www.mindful-sparks.com

Mixed and Augmented Reality as a 3D Analysis and Data Collection Tool for Archaeological Excavations / Ararat Plain Southeast Archaeological Project (APSAP)

This project develops a novel approach to managing information in archaeological excavations. The use of Mixed and Augmented Reality headsets provides 3D visual information in a way that has never been seen before. Different contexts excavated years apart can be revisited and studied in original locations in three dimensions. AR smart glasses help archaeologists record textual and photographic information through voice commands and AI agents without occupying their hands. Further laboratory work to organize notes and save information is no longer necessary.

Professor Peter J. Cobb, Associate Professor, School of Humanities, Faculty of Arts, HKU
Mr. Hayk Azizbekyan, PhD Candidate, School of Humanities, Faculty of Arts, HKU

Learn more: http://openarchaeology.org/armenia

Monexus Innovation

PerioMag is a personalised magnetic aligner system that delivers living magnetic probiotics directly to periodontal lesions. By combining magnetic guidance, local retention and microbiome modulation, it aims to provide a non-invasive, targeted and rapid treatment for periodontitis, improving drug delivery efficiency and patient compliance.

Xu Miao, PhD Student, Department of Mechanical Engineering, The University of Hong Kong

MoodBox Limited 心晴盒子有限公司

MoodBox is a design-led social enterprise on a mission to break the stigma around mental health through relatable characters and thoughtful tools. The team personifies common mental health conditions into original IP characters including Demi (depression), Anxi (anxiety), Odie (ODD), and Zippy (ADHD). Combined with emotional toolboxes and an anonymous storytelling platform called "Messages in a Bottle", MoodBox makes emotional struggles feel less isolating and more understood. The team believes that accepting every emotion is the first step toward healing.

Miss. YU YINGQI (YoYo), Co-founder & Business Director of MoodBox Ltd., Master of Social Work, Department of Social Work and Social Administration, Faculty of Social Sciences, The University of Hong Kong
Mr. LEUNG HIU YEUNG (Thomas), Co-founder & Product Designer of MoodBox Ltd., Bachelor of Engineering Graduate, Department of Civil Engineering, Faculty of Engineering, The University of Hong Kong

Learn more:
Instagram/Facebook: moodbox_hk

Multera Limited

This project develops a rapid, culture-free molecular diagnostic platform for severe infectious diseases such as sepsis. By integrating droplet microfluidics with proprietary Melting Temperature Barcoding technology, the system enables highly multiplexed and sensitive pathogen detection directly from blood samples within four hours. The platform supports absolute quantification and antimicrobial resistance identification in a streamlined sample-in, data-out workflow.

Professor Anderson Shum, Faculty of Engineering

Next Generation Intranasal Live-Attenuated Vaccine for Broad Influenza Protection by C2iVax Limited

This project develops a next-generation broadly protective intranasal influenza vaccine using two innovative technologies: alpha-Gal expressing virus for broad and robust immunity, and shifted codon usage bias for enhanced safety. The vaccine protects against multiple influenza subtypes, including human and avian strains with pandemic potential. It eliminates the need for annual reformulation and uses needle-free intranasal administration, providing added mucosal immunity in the respiratory tract.

Professor Leo POON, Chair Professor, School of Public Health, Li Ka Shing Faculty of Medicine, HKU

Learn more: www.c2ivax.hk

Open Ocean Engineering Limited (Clearbot)

Clearbot is an AI-powered autonomous electric surface vessel built to transform waterway management. It performs floating waste collection, aquatic vegetation removal, hydrographic and draft surveys, and environmental monitoring with minimal human intervention. Equipped with computer vision, robotics, and a cloud-based dashboard, Clearbot delivers real-time operational insights while improving efficiency, reducing emissions, and lowering maintenance costs. It enables ports, municipalities, industries, and environmental organizations to maintain cleaner, safer, and more sustainable waterways through intelligent, data-driven operations.

Mr. Sidhant Gupta, Co-Founder & CEO
Mr. Utkarsh Goel, Co-Founder & CTO

Learn more: http://www.clearbot.org/

PDOHub™ Organoid-Based Companion Diagnostic Centre by BiomOrgan Limited

PDOHub™ Hong Kong, Asia's First Integrated Organoid-Based Precision Medicine Centre established by BiomOrgan and InnoHK CVVT, delivers scalable, quality-assured organoid platforms that advance therapeutic development and clinical decision-making across oncology, infectious diseases, and emerging health challenges. By driving patient-derived organoid technologies and companion diagnostics that generate functional, high-resolution insights, PDOHub empowers researchers and clinicians to accelerate discovery, guide optimal treatment strategies, and achieve real-world translational impact.

Professor ZHOU Jie, Associate Professor, Department of Microbiology, School of Clinical Medicine, HKUMed

Learn more: https://www.pdohubhk.com/

Pearl Power Research Limited

Pearl Power Research Institute develops scientifically proven detoxification supplements using advanced pearl powder. Its innovative formula supports liver metabolism and activates the body's natural detox mechanisms to effectively eliminate heavy metals accumulated through the food chain and environmental exposure. This natural solution offers superior bioavailability for optimal health and wellness.

Professor Billy KC Chow, Professor, Chair of Endocrinology, School of Biological Sciences, Faculty of Science
Dr. Yan Wa Tat, CEO, PhD, School of Biological Sciences, Faculty of Science

Learn more: http://www.pprirhk.com/

PeckPerk – AI-Powered Backyard Nature Exploration Platform

WiseForge commercialises PeckPerk, an AI-powered nature exploration platform that turns backyards into interactive wildlife observatories. Its solar-powered smart bird feeders combine high-definition imaging, AI species recognition and a mobile app to capture visits, send real-time alerts and build personalised wildlife records. By making birdwatching easier, more educational and shareable, PeckPerk helps families reconnect with nature while creating a scalable foundation for broader backyard ecology monitoring and future smart plant-care products.

Mr. Zhengxi (Jason) CHEN, Founder & CEO, WiseForge Innovative Technologies Limited; MBA Alumnus, HKU Business School

Learn more: https://peckperk.com

Performance X

Performance X develops precision microbiome therapeutics for elite Thoroughbred racehorses. Using proprietary probiotic-synbiotic formulations built from beneficial bacterial strains isolated from healthy Thoroughbred racehorses, the platform restores and maintains gut health, reduces digestive disorders such as colic, and supports peak athletic performance. An AI-powered diagnostic dashboard tracks each horse's microbiome and converts data into actionable insights.

Brian Worthington

Learn more: https://www.performancexbiome.com

Pingo

PINGO serves organizations in regulated, trust-sensitive industries including insurance, financial services, healthcare, and other sectors where incorrect answers carry significant consequences. Its two-tier guardrail architecture grounds every answer in verified client knowledge, preventing hallucinations and unsafe output. The platform automates customer service while preserving accuracy, compliance, and trust.

Jack CHAN, CEO

Learn more: https://magoai.hk

PipeScan AI Limited

PipeScan AI is a Hong Kong deep-tech startup transforming underground infrastructure inspection. Our autonomous robotic carriers, equipped with LiDAR and smart sensors, navigate pipelines, tunnels and confined spaces without human entry, while our proprietary AI analytics platform performs 3D scanning and automatic defect detection of cracks, settlement and leakage. Integrated with digital twins and BIM, the solution delivers safer, faster and more accurate inspections, enabling predictive maintenance and data-driven asset management for government departments and infrastructure owners.

Mr. Lawrence WONG, Co-Founder & CEO, PipeScan AI Limited
Mr. Stephen Go, Co-Founder & Co-CEO, PipeScan AI Limited
Mr. Lentz CHUN, Co-Founder & COO, PipeScan AI Limited

Learn more: https://pipescanai.com

PressLogic Limited

MediaLens is PressLogic's proprietary AI-powered social listening and marketing intelligence platform. It continuously tracks brand mentions, trends and sentiment across Facebook, Instagram, YouTube, Xiaohongshu and local forums such as LIHKG, turning fragmented social data into actionable insight. Marketers can benchmark competitors, discover influencers, analyse winning ad campaigns and receive real-time crisis alerts, while the MediaLens AI Agent generates data-driven strategies and ready-to-publish content. The platform powers PressLogic's own media network of over 20 million followers across Asia.

Mr. Ryan CHEUNG, Founder & CEO, PressLogic Limited (BBA in Accounting & Finance 2011, Faculty of Business and Economics, HKU)
Mr. Edward CHOW, Founder & CTO, PressLogic Limited (BBA in Information Systems 2012, Faculty of Business and Economics, HKU)

Learn more: https://medialens.io

Production of Human Pluripotent Stem Cell-derived Islet Organoid for Diabetes Treatment

Nordia develops personal and universal islet organoids generated from stem cells using a patented method that enables spontaneous formation of 3D islet structures. Gene editing and T-cell co-culture reduce immunogenicity. The islet organoids are transplanted with biomaterial scaffolds for long-term control of blood glucose levels through steady insulin secretion. Nordia also provides islet-based research services.

Professor Zhongjun ZHOU, Chui Fook-Chuen Professor in Molecular Medicine, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine

Learn more: http://nordiabio.com/

Prompify

ReGen Technology

ReGen Technology Holdings Limited develops solar-powered desalination systems that convert ocean water into usable freshwater for agriculture, people, and off-grid applications. Based in Hong Kong, the company focuses on scalable, energy-efficient solutions designed for water-scarce and coastal regions worldwide. By integrating regenerative technology principles, ReGen aims to support sustainable farming, ecosystem restoration, and resilient water infrastructure.

Julian B Gaertne

Learn more: regen.technology

Resture: Active Smart Pillow for Dynamic Sleep Support

Resture is an active smart pillow that aims to dynamically improve sleep support through integrated sensing and adjustable airbag technology. Unlike conventional pillows with fixed shapes, Resture adapts to changes in sleeping positions and provides personalised support for the head and neck. The project focuses on creating a compact, comfortable, and integrated smart pillow system.

Kate Wiliem, Team Leader and Undergraduate Student, Faculty of Engineering, The University of Hong Kong
Jessica Ou, Undergraduate Student, Faculty of Engineering, The University of Hong Kong
Eden Winner Gozali, Undergraduate Student, Faculty of Engineering, The University of Hong Kong
Lok Chi Chan, Undergraduate Student, Faculty of Engineering, The University of Hong Kong
Vaylin Theron, Undergraduate Student, Faculty of Engineering, The University of Hong Kong
Lucy Tansi, Undergraduate Student, Faculty of Engineering, The University of Hong Kong

School of Innovation

This is an entrepreneurship internship programme, connecting students with startup founders to develop entrepreneurial skills. The programme fosters innovation and provides practical experience with startups, social ventures, and innovative companies. Internships last 8 weeks to a year, paid or unpaid, part-time or full-time. Students who complete the program and meet requirements earn one credit under the Credit Award Scheme for Out-of-classroom Learning Experiences.

Shenzhen Stella Robot Technology Co., Limited

Founded in August 2024, Stella Robot is an emerging global leader in embodied intelligent manipulation. The company owns full-stack self-developed embodied AI algorithm and hardware technologies and has launched the world's first drive-hand separation tendon-driven dexterous hand deployed in industrial scenarios, as well as the world's first Lego-style modular direct-drive hand tailored for industrial and high-risk scenarios. The team integrates industrial commercialization and R&D capabilities and upholds the mission of technology for good.

Mr. Dehao WEI, Founder & CEO, Shenzhen Stella Robot Technology Co., Limited

Learn more: http://www.stella-robot.com/

SightTorch Technology Limited
 
SightTorch Technology is dedicated to resolving critical pain points in Hong Kong's healthcare system, specifically the severe shortage of ophthalmologists and the excessively long waiting times for specialist outpatient services. SightTorch has developed 1) a multi-modal multi-disease AI diagnostic system to enable referral decision making without an ophthalmologist; and 2) a 24/7 intelligent patient management system for real-time health monitoring. The company strives to cut specialist outpatient waiting times by over 90% while significantly reducing cases of preventable vision loss.
 
Professor Christopher K.S. LEUNG, Chairperson and Clinical Professor, Department of Ophthalmology, School of Clinical Medicine

SNAPP OCEAN DATA SOLUTIONS LIMITED

Solefit Care Limited

SoleFit is a preventative care solution for foot pain. By training its diagnostic model on Asian foot morphologies, it eliminates Western data bias while achieving 94% accuracy. The platform replaces expensive clinical hardware with SoleScan, a LiDAR-enabled iPhone app that captures high-fidelity 3D foot scans and kinematic data. It automates diagnosis, custom insole design, and 3D printing fulfillment, making clinical-grade foot care accessible and scalable.

Vinita Turakhia, Founder & CEO

Learn more: https://solefitcare.com/

Speakable

SpeakAble HK is an AI-powered assistant tool for everyday Cantonese speech practice at home. Using voice cloning, learners practise with a familiar voice reference and repeat targeted speaking tasks in a low-pressure environment. The web app helps families build consistent routines and provides progress records that can be reviewed with teachers and speech therapists.

Ariel Chow

Learn more: https://speakable.hk

Strata Biolab Limited

Strata Bio develops an AI-powered platform that integrates proprietary multi-omics data with intelligent agents to accelerate drug target discovery. The platform enables rapid and precise identification of novel targets and target combinations in oncology and immunology at five times the speed of traditional R&D workflows. Leveraging AI agents and proprietary metabolomics data, it accelerates pharmaceutical development while reducing risk.

Professor Kevin Kin Man TSIA, Professor, Department of Electrical & Computer Engineering (joint appointment with School of Biomedical Engineering), Faculty of Engineering

SWITCH: Social Worker Interactive Training Chatbot

SWITCH is an interactive, LLM-powered chatbot designed for social work education. Using the Motivational Interviewing framework, it simulates diverse, high-risk client scenarios to offer trainees a safe, realistic practice environment. The system features an automated skills classification model that tracks communication metrics, delivering personalized feedback and objective evaluations to effectively enhance students' clinical counseling competencies.

Dr. Johnson CS Cheung, Senior Lecturer, Department of Social Work and Social Administration, Faculty of Social Sciences
Professor Ben Kao, Professor, School of Computing and Data Science
Dr. Kevin Wu, Lecturer, Tam Wing Fan Innovation Wing, Faculty of Engineering

SynHealer

Liver cancer ranks among the world's deadliest cancers, and traditional cell therapies struggle to penetrate solid tumours. SynHealer, a spin-off from the Centre for Translational Stem Cell Biology, has developed an off-the-shelf immune cell therapy for solid tumours. Its Antibody Chimeric Antigen Receptor-Macrophage (AB-CAR-M) technology engineers macrophages to secrete antibodies and break down tumour barriers, improving immune cell penetration and tumour-killing efficacy.

SYNTERFACE Biomed Technology (DentoSeal)

From dentures to wounds, current oral solutions are either ineffective or unsafe. DentoSeal, a medical-grade bioadhesive, can form an instant, tough seal on wet tissues, providing long-lasting adhesion while actively promoting healing. Its universal applications range from stabilizing dentures to reversibly fixing surgical guides, sealing peri-implant tissues, and closing wounds without sutures. It represents a new category of therapeutic bioadhesives for comprehensive oral care with enhanced user convenience and clinical flexibility.

Professor Dan Kiho, CHO

The Beverage Code (Sodaz)

Sodaz transforms surplus, imperfect and food-processing fruit by-products into premium beverages. Its whole-fruit approach creates juices, smoothies, craft fruit teas and functional drinks from pulp, skins and seeds that would otherwise be discarded. Gentle, low-temperature processing preserves flavour, nutrients and bioactive compounds, while a pilot automated aluminium bottling facility in Yuen Long supports scalable local production and collaboration with farmers and juice manufacturers.

Aaron Pang, Co-founder & CEO
Kethena Tang, Co-founder & COO
Alex Pang, Co-founder & CFO

Learn more: https://www.ne8tfoodtech.com

Voice-to-Compliance Fraud Detection by Fano Labs Limited

Fano's Voice-to-Compliance and Fraud Detection solution helps regulated enterprises make customer interactions safer, more compliant, and more trustworthy. It uses multilingual speech recognition, speaker diarization, voice biometrics, and deepfake detection to analyse calls, verify speaker identity, detect impersonation risks, and check whether required scripts or disclosures are followed. The solution supports audit-ready reporting and helps compliance, risk, and operations teams reduce manual review workload.

Dr. Miles Wen, CEO & Co-Founder of Fano Labs Limited
Honorary Assistant Professor in EEE, HKU

Learn more: https://fano.ai

Wafer-Scale Flexible Diamond Membranes

While diamond is recognized as the ultimate material for high-power semiconductors and extreme heat dissipation, its commercialization is severely hindered by high manufacturing costs, limited wafer sizes, and extreme processing difficulties. DiamNEX solves this bottleneck through a globally pioneering growth-cropping-exfoliation technique. This innovation enables scalable, low-cost production of wafer-scale, ultra-flat, and flexible diamond membranes fully compatible with existing semiconductor processes.

Professor Zhiqin CHU, Associate Professor (joint appointment with School of Biomedical Sciences), Department of Electrical and Computer Engineering, Faculty of Engineering

Δ42PD1 Antibody: A Novel Immunotherapy Against Cancers

Orimmune Biotech Ltd. is pioneering a first-in-class antibody therapy targeting Δ42PD1, a novel immune checkpoint distinct from classical PD-1. Unlike PD-1, Δ42PD1 promotes tumour growth by driving inflammation and is unaffected by current anti-PD-1 therapies. The anti-Δ42PD1 antibody has demonstrated effective tumour suppression in multiple anti-PD-1-resistant liver cancer models, offering new hope for hepatocellular carcinoma patients.

Professor Zhiwei CHEN, Director of the AIDS Institute and Chair Professor, Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, Suen Chi-Sun Professor in Clinical Science

Learn more: linkedin.com/company/orimmune-biotech-limited